Abstract | BACKGROUND: MATERIALS AND METHODS: The Romanian subjects were selected from two age groups: 20-29 years (n = 219) and 30-39 years (n = 229), representative for all counties of Romania. The commercial kit Anti- Diphtheria Toxoid ELISA ( IgG) (EUROIMMUN) was used to detect the antibodies of IgG class against diphtheria toxoid in the sera obtained from our subjects. RESULTS: We detected a 56.6% rate of positive sera (> 0.1 IU/ml--protection level) for the 20-29 age group and 31.7% positivity for the 30-39 age group. These data show a low protection level against diphtheria of the Romanian adult population, which decreases with age. The serologic data on preventable vaccine diseases are useful in order to evaluate the success of the immunization programs.
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Authors | Cristiana Cerasella Dragomirescu, Ileana-Luminiţa Coldea, Anamaria Ilie, Aurora Stănescu, Vasilica Ungureanu, Mircea Ioan Popa |
Journal | Roumanian archives of microbiology and immunology
(Roum Arch Microbiol Immunol)
2014 Jan-Jun
Vol. 73
Issue 1-2
Pg. 18-24
ISSN: 1222-3891 [Print] Romania |
PMID | 25518566
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Age Factors
- Antibodies, Bacterial
(blood)
- Corynebacterium diphtheriae
(immunology)
- Diphtheria
(epidemiology)
- Humans
- Romania
(epidemiology)
- Seroepidemiologic Studies
- Young Adult
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