An extraordinary case of mesenchymal chondrosarcoma metastasis in the thyroid.

Abstract

Secondary tumours of the thyroid gland account for 1.25 to 3 % in clinical series and reach 24 % in autopsy series. Chondrosarcoma is a rare malignant mesenchymal tumour of chondrogenic nature; the mesenchymal variant represents less than 3 % of all chondrosarcomas, being therefore extremely rare. A mesenchymal chondrosarcoma metastasis in the thyroid is exceptional; to our knowledge, only three previous cases of chondrosarcoma metastasis in the thyroid have been reported to date but none of such cases corresponded to a mesenchymal chondrosarcoma. We present the first of such a case in a 27-year-old woman with a 4-year history of mesenchymal chondrosarcoma of the sacrum that was treated by surgery and chemotherapy. At the present admission, head and neck computed tomography revealed a well-defined nodule in the thyroid gland. The diagnosis of metastasis from the mesenchymal chondrosarcoma was made in the right lobectomy specimen.

• Authors: Santiago Ortiz, Francisco Tortosa, Manuel Sobrinho Simões
• Journal: Endocrine pathology (Endocr Pathol) Vol. 26 Issue 1 Pg. 33-6 (Mar 2015) ISSN: 1559-0097 [Electronic] United States
• PMID: 25510635 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Antineoplastic Agents (therapeutic use)
• Bone Neoplasms (pathology, surgery)
• Cartilage (pathology)
• Chondrosarcoma, Mesenchymal (pathology, secondary, surgery)
• Female
• Humans
• Sacrum
• Thyroid Neoplasms (pathology, secondary)
• Thyroidectomy