Abstract |
Sleep-related eating disorder (SRED) is a condition characterized by recurrent episodes of eating at the transition from night-time sleep to arousal. SRED patients describe eating in an out-of-control manner with preference for high-caloric foods and sometimes with inedible or toxic items. Level of consciousness during SRED episodes ranges from partial consciousness to dense unawareness typical of somnambulistic episodes. SRED is sometimes associated with psychotropic medication, in particular sedative hypnotics, and other sleep disorders, including parasomnias, narcolepsy, and restless legs syndrome. Night eating syndrome (NES) is another important condition in the disordered night-time eating spectrum showing hyperphagia episodes at full arousal from nocturnal sleep without accompanying amnesia. NES could be considered an abnormality in the circadian rhythm of meal timing with a normal circadian timing of sleep onset. The two conditions often overlap and possibly share a common pathophysiology. Studies have suggested that central nervous system serotonin modulation may lead to an effective treatment of NES, while the anti-seizure medication topiramate may be an effective SRED treatment.
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Authors | Yuichi Inoue |
Journal | Psychiatry and clinical neurosciences
(Psychiatry Clin Neurosci)
Vol. 69
Issue 6
Pg. 309-20
(Jun 2015)
ISSN: 1440-1819 [Electronic] Australia |
PMID | 25495278
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Copyright | © 2014 The Author. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology. |
Chemical References |
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Topics |
- Comorbidity
- Feeding and Eating Disorders
(chemically induced, diagnosis, epidemiology, physiopathology)
- Humans
- Hyperphagia
(chemically induced, diagnosis, epidemiology, physiopathology)
- Hypnotics and Sedatives
(adverse effects)
- Mental Disorders
(epidemiology)
- Narcolepsy
(epidemiology)
- Parasomnias
(chemically induced, diagnosis, epidemiology, physiopathology)
- Restless Legs Syndrome
(epidemiology)
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