Stimuli-responsive polymers for anti-cancer drug delivery.

Abstract

Stimuli-responsive polymers are an important component for preparation of stimuli-responsive drug delivery systems with less side effects and improved efficacy for cancer treatment. There are endogenous stimuli and exogenous stimuli which can be explored. Here we review the developments in both endogenous stimuli- including redox-/pH-/enzyme-responsive polymers and exogenous stimuli- including thermo-/photo- and ultrasound-responsive polymers for delivery of anti-cancer drugs.

• Authors: Weiren Cheng, Liuqun Gu, Wei Ren, Ye Liu
• Journal: Materials science & engineering. C, Materials for biological applications (Mater Sci Eng C Mater Biol Appl) Vol. 45 Pg. 600-8 (Dec 2014) ISSN: 1873-0191 [Electronic] Netherlands
• PMID: 25491870 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: Copyright © 2014 Elsevier B.V. All rights reserved.

Chemical References

• Antineoplastic Agents
• Drug Carriers
• Polymers
• Glutathione

Topics

• Antineoplastic Agents (administration & dosage, chemistry)
• Drug Carriers (chemistry)
• Glutathione (chemistry, metabolism)
• Humans
• Hydrogen-Ion Concentration
• Neoplasms (drug therapy)
• Oxidation-Reduction
• Polymers (chemistry)
• Temperature