Herpes simplex virus infection during pregnancy.

Abstract

Genital herpes in pregnancy continues to cause significant maternal morbidity, with an increasing number of infections being due to oral-labial transmission of herpes simplex virus (HSV)-1. Near delivery, primary infections with HSV-1 or HSV-2 carry the highest risk of neonatal herpes infection, which is a rare but potentially devastating disease for otherwise healthy newborns. Prevention efforts have been limited by lack of an effective intervention for preventing primary infections and the unclear role of routine serologic testing.

• Authors: Alyssa Stephenson-Famy, Carolyn Gardella
• Journal: Obstetrics and gynecology clinics of North America (Obstet Gynecol Clin North Am) Vol. 41 Issue 4 Pg. 601-14 (Dec 2014) ISSN: 1558-0474 [Electronic] United States
• PMID: 25454993 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2014 Elsevier Inc. All rights reserved.

Chemical References

• Antiviral Agents

Topics

• Adolescent
• Adult
• Antiviral Agents
• Cesarean Section
• Female
• Herpes Genitalis (immunology, prevention & control, transmission)
• Herpes Simplex (immunology, prevention & control, transmission)
• Herpesvirus 1, Human (isolation & purification)
• Herpesvirus 2, Human (isolation & purification)
• Humans
• Infant, Newborn
• Infectious Disease Transmission, Vertical (prevention & control)
• Nutrition Surveys
• Practice Guidelines as Topic
• Pregnancy
• Pregnancy Complications, Infectious (immunology, prevention & control)
• Prevalence
• Seroepidemiologic Studies
• United States (epidemiology)