Pancreaticogastrostomy or pancreaticojejunostomy? Methods of digestive continuity reconstruction after pancreaticodudenectomy: a meta-analysis of randomized controlled trials.

Abstract

BACKGROUND AND AIMS:

Reconstruction of digestive tract after pancreaticodudenectomy now has been proved associated with pancreatic fistula and complication incidence. The meta-analysis was conducted at the appropriate time enough randomized controlled trials were reported.

METHODS:

Systematically literature search was performed through PubMed, EMBASE and Cochrane Library database without restriction to regions, or languages, only randomized controlled trials was included. 7 studies compared pancreatogastrostomy with pancreaticojejunostomy were included for meta-analysis. Fixed and random-effects models were used to measure the pooled estimates.

RESULTS:

Patient underwent pancreatogastrostomy after pancreatoduodenectomy suffered less pancreatic fistula(p = 0.001) and bile leakage (p = 0.02), while the operative time, hospital stay, delayed gastric emptying and overall morbidity were comparable.

CONCLUSION:

Pancreatogastrostomy is a recommended anastomosis technique according to the meta-analysis due to minimize incidence of pancreatic fistula and bile leakage.

• Authors: Purun Lei, Jiafeng Fang, Yong Huang, Zongheng Zheng, Bo Wei, Hongbo Wei
• Journal: International journal of surgery (London, England) (Int J Surg) Vol. 12 Issue 12 Pg. 1444-9 (Dec 2014) ISSN: 1743-9159 [Electronic] United States
• PMID: 25448669 (Publication Type: Journal Article, Meta-Analysis, Review)
• Copyright: Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Topics

• Anastomotic Leak (etiology, prevention & control)
• Bile
• Gastrostomy (methods)
• Humans
• Incidence
• Length of Stay
• Operative Time
• Pancreas (surgery)
• Pancreatic Fistula (etiology, prevention & control)
• Pancreaticoduodenectomy (adverse effects)
• Pancreaticojejunostomy (adverse effects, methods)
• Randomized Controlled Trials as Topic
• Plastic Surgery Procedures (adverse effects, methods)