Using cost-effective intra-arterial chemotherapy to treat retinoblastoma in Chile.

Abstract	Intra-arterial chemotherapy (IAC) has proved to be an effective treatment for retinoblastoma, but can be very expensive in developing countries. We report 2 patients from Chile in whom IAC resulted in globe salvation. Both patients had their medical care provided by the public health system and had failed standard therapy.
Authors	Diego Ossandón, Mario Zanolli, Verónica Pérez, Paulo Zúñiga, Álvaro Belmar, Mónica Varas, Carol L Shields
Journal	Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 18 Issue 6 Pg. 617-9 (Dec 2014) ISSN: 1528-3933 [Electronic] United States
PMID	25448150 (Publication Type: Journal Article)
Copyright	Copyright © 2014 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.
Chemical References	Topotecan Melphalan
Topics	Adolescent Antineoplastic Combined Chemotherapy Protocols (economics, therapeutic use) Chile Cost-Benefit Analysis Developing Countries Drug Costs Humans Infant Infusions, Intra-Arterial (economics) Male Melphalan (administration & dosage) Retinal Neoplasms (drug therapy, pathology) Retinoblastoma (drug therapy, pathology) Topotecan (administration & dosage)

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