Abstract | INTRODUCTION: OBJECTIVE: To review the cases of MCUL diagnosed at 2 university hospitals over a 5-year period (2008-2013). MATERIAL AND METHODS: This was a retrospective study of 13 cases of MCUL that investigated demographic, clinical, and histologic characteristics, as well as possible associations with other diseases and treatments received. RESULTS: We identified 13 patients (10 women and 3 men) who had been diagnosed with MCUL. The mean age at diagnosis was 53 years. All the patients had multiple cutaneous leiomyomas; in 12 (92%) the distribution was clustered and 9 (69%) also had disseminated solitary lesions. In 1 patient (7.7%), the pattern of distribution was linear. Uterine fibroids requiring hysterectomy were present in 90% of the women. Nine patients were screened for renal lesions; no cases of renal cell carcinoma were detected but benign renal lesions were found in 4 patients. CONCLUSION: The clinical and histologic characteristics of the 13 cases of MCUL reviewed were similar to those reported in the literature. The most common cutaneous manifestation was a type 2 segmental pattern. It is important for dermatologists to identify cutaneous leiomyomas and be aware of the possible association with MCUL.
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Authors | H Collgros, M Iglesias-Sancho, M J Tribó-Boixareu, L Creus-Vila, P Umbert-Millet, M Salleras-Redonnet |
Journal | Actas dermo-sifiliograficas
(Actas Dermosifiliogr)
Vol. 106
Issue 2
Pg. 117-25
(Mar 2015)
ISSN: 1578-2190 [Electronic] Spain |
PMID | 25439147
(Publication Type: Journal Article, Multicenter Study)
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Copyright | Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved. |
Topics |
- Adult
- Aged
- Female
- Humans
- Leiomyomatosis
(pathology, therapy)
- Male
- Middle Aged
- Neoplastic Syndromes, Hereditary
- Retrospective Studies
- Skin Neoplasms
(pathology, therapy)
- Uterine Neoplasms
(pathology, therapy)
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