Abstract | BACKGROUND: MATERIALS AND METHODS: Orthogonal experiment, UV spectrophotometry and conventional antilipemic effect determination method were used to optimize the extraction process, and to determine the total anthraquinone content, as well as blood levels of total cholesterol, triglycerides, HDL and LDL. RESULTS: CONCLUSION: The optimum extraction process was two times extraction of Radix et Rhizoma rhei with 70% ethanol, the amounts of solvent of 8 folds and 5 folds, successively, and the extraction time of 60 min each. In addition, this extract has an antilipemic effect in mice.
|
Authors | Hui-Chun Xie, Jun Shang |
Journal | African journal of traditional, complementary, and alternative medicines : AJTCAM
(Afr J Tradit Complement Altern Med)
Vol. 11
Issue 2
Pg. 358-62
( 2014)
ISSN: 2505-0044 [Electronic] Nigeria |
PMID | 25435622
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Anthraquinones
- Drugs, Chinese Herbal
- Hypolipidemic Agents
|
Topics |
- Animals
- Anthraquinones
(administration & dosage, analysis, isolation & purification)
- Drugs, Chinese Herbal
(administration & dosage, analysis, isolation & purification)
- Female
- Humans
- Hyperlipidemias
(drug therapy, metabolism)
- Hypolipidemic Agents
(administration & dosage, analysis, isolation & purification)
- Male
- Mice
- Rheum
(chemistry)
- Rhizome
(chemistry)
|