[Enolase and parasitic infection].

Abstract

Enolase is one kind of important glycolytic enzymes which widely exists in most organisms. A number of recent studies confirm that this enzyme has the functions of activating the plasminogen, involving in the processes of infection and migration of parasites, reducing the immune function of the host as well as preventing parasites from the immune attack of the host. This paper reviews the current research advances in the parasite enolase, and explores its potential for diagnosis, drug development and vaccine target of parasitic diseases.

• Authors: Hong Gao, Chuan-xin Yu
• Journal: Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control (Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi) Vol. 26 Issue 4 Pg. 445-8 (Aug 2014) ISSN: 1005-6661 [Print] China
• PMID: 25434150 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Plasminogen
• Phosphopyruvate Hydratase

Topics

• Amino Acid Sequence
• Animals
• Humans
• Molecular Sequence Data
• Parasitic Diseases (enzymology, immunology, metabolism)
• Phosphopyruvate Hydratase (chemistry, metabolism)
• Plasminogen (metabolism)