Abstract |
The aim of this paper is to summarise the blocking effects of parthenolide on the cytokines and pathways that cause inflammation. Analyses of the chemical structure of parthenolide have tried to identify the active domains that play key roles in its anti-inflammatory activity. This review focuses on the anti-inflammatory actions of parthenolide in both in vitro and in vivo. These data will be helpful for future investigations into the effects of parthenolide on inflammation.
|
Authors | Mengting Wang, Qiyan Li |
Journal | Natural product research
(Nat Prod Res)
Vol. 29
Issue 12
Pg. 1092-101
( 2015)
ISSN: 1478-6427 [Electronic] England |
PMID | 25429885
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
|
Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Cytokines
- Sesquiterpenes
- parthenolide
|
Topics |
- Animals
- Anti-Inflammatory Agents, Non-Steroidal
(pharmacology)
- Cytokines
(metabolism)
- Humans
- Inflammation
(drug therapy)
- Sesquiterpenes
(pharmacology)
|