Clinical study on Kangquan Recipe (康泉方) for benign prostatic hyperplasia patients: a randomized controlled trial.

Abstract

OBJECTIVE:

To observe the effectiveness and safety of Kangquan Recipe (康泉方, KQR) for benign prostatic hyperplasia (BPH) patients.

METHODS:

One hundred and six BPH patients were randomly assigned to the treatment group (53 cases) and the control group (53 cases) according to a random number table. The treatment group was given KQR orally; the control group was given cernilton orally. After 24-week treatment, the clinical effect and safety were evaluated using the International Prostatic Symptom Score (I-PSS), quality of life (QOL), maximum flow rate (Qmax), average flow rate (Qave), residual urine volume (RUV), total prostatic volume (TPV), etc.

RESULTS:

After treatment, the score of I-PSS was decreased from 16.9±5.6 to 12.5±4.6 in the treatment group, significantly lower compared with the control group; the levels of Qmax and Qave were from 10.9±3.5 to 15.6±4.5 and 5.4±2.1 to 7.3±2.5 (mL/s) in the treatment group, significantly higher compared with the control group; the levels of RUV and TPV were from 70.8±28.2 to 35.2±21.8 and 37.2±16.9 to 30.1±10.8 (mL) in the treatment group, significantly lower compared with the control group (all P<0.05). The incidence rate of adverse reaction was similar between the two groups (P>0.05).

CONCLUSION:

KQR is effective and safe for the treatment of BPH.

• Authors: Yuan-peng Huang, Yan-hui Wen, Geng-hui Wu, Zhen-feng Hong, Shang-wen Xu, A-xiang Peng
• Journal: Chinese journal of integrative medicine (Chin J Integr Med) Vol. 20 Issue 12 Pg. 949-54 (Dec 2014) ISSN: 1672-0415 [Print] China
• PMID: 25428342 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Drugs, Chinese Herbal
• kangquan

Topics

• Aged
• Drugs, Chinese Herbal (adverse effects, therapeutic use)
• Humans
• Male
• Middle Aged
• Organ Size
• Prostate (pathology)
• Prostatic Hyperplasia (drug therapy, physiopathology, urine)
• Treatment Outcome
• Urination