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The evaluation of olfactory function in individuals with chronic halitosis.

Abstract
Halitosis and olfactory dysfunction may disrupt an individual's quality of life remarkably. One may ask whether halitosis has effects on olfactory functions or not? Thus, the aim of this study was to evaluate the olfactory abilities of subjects with chronic halitosis evaluated using the measurements of volatile sulfur compounds. This study was carried out in 77 subjects, with a mean age of 40.1±13.3 years, ranging from 18 to 65 years. Forty-three participants were diagnosed as halitosis according to the gas chromatography results and constituted the halitosis group. Also, a control group was created from individuals without a complaint of halitosis and also who had normal values for volatile sulfur compounds. Each subject's orthonasal olfactory and retronasal olfactory functions were assessed using "Sniffin' Sticks" and retronasal olfactory testing. The results showed that odor threshold scores were lower in participants with halitosis compared with controls. Also, hyposmia was seen more common in the halitosis group than in controls. Moreover, a significant negative correlation was found between odor threshold scores and volatile sulfur compounds levels, particularly with hydrogen sulfide and dimethyl sulfide levels. The results suggest that the chronic presence of volatile sulfur compounds may have a negative effect on olfactory function.
AuthorsAytug Altundag, Melih Cayonu, Gurkan Kayabasoglu, Murat Salihoglu, Hakan Tekeli, Sibel Cayonu, Meltem Esen Akpinar, Thomas Hummel
JournalChemical senses (Chem Senses) Vol. 40 Issue 1 Pg. 47-51 (Jan 2015) ISSN: 1464-3553 [Electronic] England
PMID25422366 (Publication Type: Journal Article)
Copyright© The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: [email protected].
Chemical References
  • Sulfhydryl Compounds
  • Sulfides
  • dimethyl sulfide
  • Hydrogen Sulfide
Topics
  • Adolescent
  • Adult
  • Aged
  • Chronic Disease
  • Female
  • Halitosis (pathology)
  • Humans
  • Hydrogen Sulfide (pharmacology)
  • Male
  • Middle Aged
  • Odorants
  • Olfaction Disorders (physiopathology)
  • Olfactory Bulb (drug effects)
  • Sensory Thresholds (drug effects)
  • Sulfhydryl Compounds (pharmacology)
  • Sulfides (pharmacology)
  • Young Adult

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