Abstract | AIM: The aim of this study was to determine clinical performance of gestrinone combined with ultrasound-guided aspiration and ethanol injection in treating chocolate cyst of ovary. METHODS: Sixty-eight patients enrolled in this study were randomly divided into two groups: control group and combination treatment group. In the control group, 34 patients were treated with ultrasound-guided aspiration and ethanol injection. In the combination treatment group, 34 patients received gestrinone p.o. following ultrasound-guided aspiration and ethanol injection. RESULTS: The recurrence rate of chocolate cyst was 10-fold lower in the combination treatment group (2.94%, 1/34) than in the control group (29.4%, 10/34) at 12 months. The effective rate for reduction of chocolate cyst was significantly higher in the combination treatment group (94.12%, 32/34) than in the control group (64.71%, 22/34) (P = 0.009). CONCLUSION:
Gestrinone combined with ultrasound-guided aspiration and ethanol injection therapy is an effective treatment for ovarian chocolate cyst with low recurrence rate.
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Authors | Xiaoyun Wu, Yun Xu |
Journal | The journal of obstetrics and gynaecology research
(J Obstet Gynaecol Res)
Vol. 41
Issue 5
Pg. 712-6
(May 2015)
ISSN: 1447-0756 [Electronic] Australia |
PMID | 25420776
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology. |
Chemical References |
- Progestins
- Gestrinone
- Ethanol
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Topics |
- Adult
- Combined Modality Therapy
- Ethanol
(therapeutic use)
- Female
- Gestrinone
(therapeutic use)
- Humans
- Middle Aged
- Ovarian Cysts
(drug therapy, surgery, therapy)
- Paracentesis
- Progestins
(therapeutic use)
- Recurrence
- Treatment Outcome
- Ultrasonography, Interventional
- Young Adult
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