Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report.

Abstract

Essential thrombocytosis (ET) is a type of myeloproliferative neoplasm with clinical manifestations of thrombosis and hemorrhage, the mechanisms of which remains unclear. Some researches indicated that ET is mainly related to the defect of platelet function and the abnormality of coagulation mechanism. A few reports showed that ET accompanied by acquired hemophilia. However, no evidence of ET with coagulation factor XII deficiency has been published. we here report a case of ET accompanied with coagulation factor XII deficiency, which had clinically significant bleeding tendency.

• Authors: Yan Wang, Zunsong Wang, Hong Li, Kehong Bi, Chuansheng Zhu
• Journal: International journal of clinical and experimental medicine (Int J Clin Exp Med) Vol. 7 Issue 10 Pg. 3725-9 ( 2014) ISSN: 1940-5901 [Print] United States
• PMID: 25419425 (Publication Type: Case Reports)