Post-renal transplant erythrocytosis: a case report.

Abstract

PTE is defined as hematocrit >51% or hemoglobin >17 g/dL after renal transplantation. Risk factors include native kidneys with adequate erythropoiesis pretransplant, smoking, renal artery stenosis, and cyclosporine treatment. We report the case of a 14-yr-old female kidney transplant patient, with triple therapy immunosuppression and stable graft function who developed PTE at 12 months post-transplant with hemoglobin 17.3 g/dL, hematocrit 54.2%, stable graft function, and normotensive with normal cardiac echocardiogram and erythropoietin levels. The only risk factor found was tobacco use. As she had no spontaneous improvement, enalapril treatment was started at 19 months post-transplant with a hemoglobin level of 17.5 g/dL and hematocrit 53%; by 23 months post-transplant, hemoglobin lowered to 15 g/dL and hematocrit to 44.5% and continued to be in normal range thereafter. PTE is a rare condition in childhood and can be successfully treated with enalapril.

• Authors: Mavel Almonte, Luis Velásquez-Jones, Saúl Valverde, Bruce Carleton, Mara Medeiros
• Journal: Pediatric transplantation (Pediatr Transplant) Vol. 19 Issue 1 Pg. E7-10 (Feb 2015) ISSN: 1399-3046 [Electronic] Denmark
• PMID: 25418869 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Topics

• Adolescent
• Female
• Humans
• Kidney Transplantation (adverse effects)
• Polycythemia (etiology)