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Retreatment using a dual mode of low-fluence Q-switched and long-pulse Nd:YAG laser in patients with melasma aggravation after previous therapy.

AbstractBACKGROUND:
Aggravated melasma after treatment is vulnerable to stimulation, can easily deteriorate, and may be distressing without proper management.
OBJECTIVE:
To retrospectively assess the effectiveness and safety of combination therapy using low-fluence Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (QSNY) and long-pulse Nd:YAG laser (LPNY) (dual toning) in patients with rebound melasma.
MATERIALS AND METHODS:
A total of 30 patients with aggravated melasma after previous therapy who were treated with dual toning were enrolled. A total of 10 sessions were conducted at 1-week intervals, followed by maintenance treatment. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) and the physician's global assessment (PGA) before and 2 months after completing the 10 treatment sessions.
RESULTS:
The baseline mMASI was 10.48 ± 3.64, which significantly decreased to 3.22 ± 1.45 2 months after completing the 10 treatment sessions (p < 0.001). Twenty-four patients (80%) had PGA grade 4 (76-100% improvement) and 6 patients (20%) had PGA grade 3 (51-75% improvement).
CONCLUSION:
Dual toning may be a safe and effective salvage treatment for patients with aggravated melasma after previous treatment. LPNY may stabilize melasma activity to prevent rebound hyperpigmentation via dermal remodeling.
AuthorsChun Pil Choi, Seon Mi Yim, Soo Hong Seo, Hyo Hyun Ahn, Young Chul Kye, Jae Eun Choi
JournalJournal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology (J Cosmet Laser Ther) Vol. 17 Issue 3 Pg. 129-34 (Jun 2015) ISSN: 1476-4180 [Electronic] England
PMID25415369 (Publication Type: Journal Article)
Topics
  • Adult
  • Asian People
  • Cosmetic Techniques
  • Female
  • Humans
  • Lasers, Solid-State (adverse effects, therapeutic use)
  • Low-Level Light Therapy (methods)
  • Melanosis (radiotherapy)
  • Middle Aged
  • Patient Satisfaction
  • Retreatment
  • Retrospective Studies

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