Feasibility of a novel colonoscope with extra-wide angle of view: a clinical study.

Abstract

BACKGROUND AND STUDY AIMS:

Lesions may be missed during colonoscopy because of anatomical features such as mucosal folds. This feasibility study assessed the safety and efficacy of a novel colonoscope with extra-wide angle of view, which provides a simultaneous lateral-backward view to complement the forward view.

PATIENTS AND METHODS:

Consecutive patients undergoing colonoscopy using the prototype colonoscope were enrolled in this multicenter, single-arm study. The number of adverse events, and the first detection of adenomas during withdrawal by the lateral-backward view and the forward view were evaluated.

RESULTS:

A total of 47 patients underwent colonoscopy examination to the cecum. The mean insertion and withdrawal times were 6.4 ± 4.9 minutes and 8.6 ± 4.2 minutes, respectively. Of 47 detected polyps, 28 adenomatous polyps were found (mean size 3.3 ± 3.1 mm). A total of 29 polyps (61.7 %) and 16 adenomatous polyps (57.1 %) were first detected with the lateral-backward view. The lateral-backward view first detected 5/6 adenomatous polyps (83.3 %) in the ascending colon and all (2/2) adenomatous polyps in the sigmoid colon. No adverse events occurred during the study.

CONCLUSIONS:

This exploratory study suggested that a novel colonoscope with extra-wide angle of view is safe and feasible, and has the potential to improve colorectal adenoma detection.

TRIAL REGISTER:

UMIN000016450.

• Authors: Toshio Uraoka, Shinji Tanaka, Shiro Oka, Takahisa Matsuda, Yutaka Saito, Tomohiko Moriyama, Reiji Higashi, Takayuki Matsumoto
• Journal: Endoscopy (Endoscopy) Vol. 47 Issue 5 Pg. 444-8 (May 2015) ISSN: 1438-8812 [Electronic] Germany
• PMID: 25412088 (Publication Type: Clinical Trial, Journal Article, Multicenter Study)
• Copyright: © Georg Thieme Verlag KG Stuttgart · New York.

Topics

• Adenoma (diagnosis)
• Aged
• Colon, Ascending
• Colon, Sigmoid
• Colonic Neoplasms (diagnosis)
• Colonic Polyps (diagnosis)
• Colonoscopes (adverse effects)
• Colonoscopy (instrumentation)
• Feasibility Studies
• Female
• Humans
• Male
• Middle Aged
• Time Factors