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N-acetylglucosaminyl 1-phosphate transferase: an excellent target for developing new generation breast cancer therapeutic.

AuthorsAditi Banerjee, Juan A Martinez, Maria O Longas, Zhenbo Zhang, Jesus Santiago, Krishna Baksi, Dipak K Banerjee
JournalAdvances in experimental medicine and biology (Adv Exp Med Biol) Vol. 842 Pg. 355-74 ( 2015) ISSN: 0065-2598 [Print] United States
PMID25408354 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Tunicamycin
  • Vascular Endothelial Growth Factor Receptor-1
  • Vascular Endothelial Growth Factor Receptor-2
  • Transferases (Other Substituted Phosphate Groups)
  • UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase
Topics
  • Animals
  • Breast Neoplasms (blood supply, drug therapy, metabolism)
  • Cell Line
  • Cell Line, Tumor
  • Cell Proliferation (drug effects)
  • DNA Fragmentation (drug effects)
  • Dose-Response Relationship, Drug
  • Endoplasmic Reticulum Stress (drug effects)
  • Female
  • Humans
  • Mice, Nude
  • Neovascularization, Pathologic (prevention & control)
  • Phosphorylation (drug effects)
  • Spectrum Analysis, Raman
  • Time Factors
  • Transferases (Other Substituted Phosphate Groups) (antagonists & inhibitors, metabolism)
  • Tumor Burden (drug effects)
  • Tunicamycin (pharmacology)
  • Vascular Endothelial Growth Factor Receptor-1 (metabolism)
  • Vascular Endothelial Growth Factor Receptor-2 (metabolism)
  • Xenograft Model Antitumor Assays

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