[Preventive effect of behavioral therapy plus flunarizine in children with migraine].

Abstract

OBJECTIVE:

To investigate the preventive effect of behavioral therapy plus flunarizine in children with migraine.

METHODS:

Ninety pediatric patients with migraine between January 2011and January 2014 were randomly divided into treatment group (45 cases) and control group (45 cases). The treatment group received behavioral therapy in addition to oral flunarizine, while the control group received oral flunarizine alone. All patients were followed up for 3 months to evaluate the therapeutic effect by the Pediatric Migraine Disability Assessment Score (PedMIDAS) and improved Bussone headache index.

RESULTS:

There were no significant differences in PedMIDAS (P>0.05) and improved Bussone headache index (P>0.05) between the control and treatment groups before treatment. Significant differences were observed in PedMIDAS (16±8 vs 20±10; P<0.05) and improved Bussone headache index (25±18 vs 37±21; P<0.05) between the two groups after 3 months of treatment.

CONCLUSIONS:

Preventive treatment of behavioral therapy plus oral flunarizine shows a better clinical efficacy than oral flunarizine alone in children with migraine and holds promise for clinical application.

• Authors: Yan-Zhao Chen, Ning Li, Ke-Ying Zhou
• Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics (Zhongguo Dang Dai Er Ke Za Zhi) Vol. 16 Issue 11 Pg. 1105-8 (Nov 2014) ISSN: 1008-8830 [Print] China
• PMID: 25406552 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Flunarizine

Topics

• Adolescent
• Behavior Therapy
• Child
• Combined Modality Therapy
• Female
• Flunarizine (therapeutic use)
• Humans
• Male
• Migraine Disorders (therapy)