Abstract |
New tools for mapping and manipulating molecularly defined neural circuits have improved the understanding of how the central nervous system regulates appetite. Studies that focused on Agouti-related protein neurons, a starvation-sensitive hypothalamic population, have identified multiple circuit elements that can elicit or suppress feeding behavior. Distinct axon projections of this neuron population point to different circuits that regulate long-term appetite, short-term feeding, or visceral malaise-mediated anorexia. Here, we review recent studies examining these neural circuits that control food intake.
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Authors | Scott M Sternson, Deniz Atasoy |
Journal | Neuroendocrinology
(Neuroendocrinology)
Vol. 100
Issue 2-3
Pg. 95-102
( 2014)
ISSN: 1423-0194 [Electronic] Switzerland |
PMID | 25402352
(Publication Type: Journal Article, Review)
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Copyright | © 2014 S. Karger AG, Basel. |
Chemical References |
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Topics |
- Agouti-Related Protein
(metabolism)
- Animals
- Anorexia
(physiopathology)
- Appetite Regulation
(physiology)
- Appetitive Behavior
(physiology)
- Brain
(physiology, physiopathology)
- Neural Pathways
(physiology)
- Neurons
(physiology)
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