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Pharmacotherapy of trichotillomania (hair pulling disorder): an updated systematic review.

AbstractINTRODUCTION:
Individuals affected by trichotillomania (TTM) (hair-pulling disorder) consciously or non-consciously pull out their own body hair. The disorder has recently been incorporated into a chapter entitled, 'Obsessive-Compulsive and Related Disorders' in the diagnostic and statistical manual of mental disorders, fifth edition.
AREAS COVERED:
The review describes the literature currently available on the pharmacotherapy for TTM, including both randomized controlled trials and open-label trials of pharmacotherapy for TTM in adults or children.
EXPERT OPINION:
Early work focused on the serotonin reuptake inhibitors; however, the majority of the trials have been negative. There is a small body of evidence focused on pharmacotherapy for TTM. In future, larger trials are required to expand on the preliminary evidence available for N-acetylcysteine, olanzapine and dronabinol in recent trials.
AuthorsRachel Rothbart, Dan J Stein
JournalExpert opinion on pharmacotherapy (Expert Opin Pharmacother) Vol. 15 Issue 18 Pg. 2709-19 (Dec 2014) ISSN: 1744-7666 [Electronic] England
PMID25399534 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review, Systematic Review)
Chemical References
  • Antidepressive Agents
  • Antipsychotic Agents
  • Narcotic Antagonists
  • Serotonin Uptake Inhibitors
  • Benzodiazepines
  • Dronabinol
  • Olanzapine
  • Acetylcysteine
Topics
  • Acetylcysteine (therapeutic use)
  • Antidepressive Agents (therapeutic use)
  • Antipsychotic Agents (therapeutic use)
  • Benzodiazepines (therapeutic use)
  • Dronabinol (therapeutic use)
  • Humans
  • Narcotic Antagonists (therapeutic use)
  • Olanzapine
  • Selective Serotonin Reuptake Inhibitors (therapeutic use)
  • Trichotillomania (drug therapy)

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