Concurrent emphysematous pyelonephritis and thigh necrotizing fasciitis after intramuscular administration of diclofenac.

Abstract

Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft tissue infection. NF may result from any injury to the skin or from hematogenous spread. However, con-current emphysematous pyelonephritis and necrotizing fasciitis of the left thigh has not been reported. We report a case of emphysematous pyelonephritis and necrotizing fasciitis of the left thigh after intramuscular administration of diclofenac that improved with aggressive management including broad-spectrum antibiotics, nephrectomy and surgical intervention.

• Authors: Fateme Shamekhi Amiri, Alireza Foroughi
• Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (Saudi J Kidney Dis Transpl) Vol. 25 Issue 6 Pg. 1263-5 (Nov 2014) ISSN: 1319-2442 [Print] Saudi Arabia
• PMID: 25394447 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents, Non-Steroidal
• Diclofenac

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage)
• Diclofenac (administration & dosage)
• Emphysema (diagnosis, microbiology, therapy)
• Escherichia coli Infections (diagnosis, microbiology, therapy)
• Fasciitis, Necrotizing (diagnosis, microbiology, therapy)
• Female
• Humans
• Injections, Intramuscular (adverse effects)
• Nephrectomy
• Pyelonephritis (diagnosis, microbiology, therapy)
• Thigh
• Treatment Outcome