HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The use of targeted percutaneous laser disc decompression under the guidance of puncture-radiating pain leads to better short-term responses in lumbar disc herniation.

AbstractOBJECTIVE:
Traditional percutaneous laser disc decompression (PLDD) eliminates nucleus pulposus in the center of lumbar discs. Targeted PLDD is an alternative technique that involves elimination and decompression of the target area located 5-8 mm in the front of the herniated disc. We aimed to compare the efficacy of targeted PLDD with traditional PLDD in the treatment of lumbar disc herniation and evaluate the usefulness of guidance by puncture-radiating pain on clinical outcomes of PLDD.
PATIENTS AND METHODS:
We treated 61 patients with lumbar disc herniation. Patients were stratified into control group, which included patients who underwent traditional PLDD, and study group in patients underwent targeted PLDD. Clinical outcomes and efficacies were evaluated at different time points using the visual analog scale (VAS) and modified MacNab criteria.
RESULTS:
Patients in the study group demonstrated significantly greater decreases in the VAS scores compared with those in control group. These differences were observed on Day 3, and 1 and 3 months after the treatment. Further, VAS scores were markedly lower in the patients whose treatment was guided by the puncture-radiating pain. Thus, at 1 month after the operation, 64.1% of those patients showed excellent or good outcomes based on MacNab criteria, which was almost twice the percentage seen in patients who did not experience the puncture-radiating pain (36.4%).
CONCLUSIONS:
Targeted PLDD is an effective, minimally invasive, and safe technique for lumbar disc herniation, and this technique achieves better short-term postsurgical outcomes than traditional PLDD. Puncture-radiating pain is an important prognostic indicator for better short-term responses to the treatment.
AuthorsD-X Luo, X-J Jin, G-T Li, H-T Sun, Y-Y Li, Y Qi
JournalEuropean review for medical and pharmacological sciences (Eur Rev Med Pharmacol Sci) Vol. 18 Issue 20 Pg. 3048-55 (Oct 2014) ISSN: 2284-0729 [Electronic] Italy
PMID25392104 (Publication Type: Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Decompression, Surgical (methods)
  • Female
  • Humans
  • Intervertebral Disc Displacement (complications, diagnostic imaging, surgery)
  • Laser Therapy (methods)
  • Lumbar Vertebrae (diagnostic imaging, surgery)
  • Male
  • Middle Aged
  • Pain (diagnostic imaging, etiology, surgery)
  • Pain Measurement (methods)
  • Prognosis
  • Punctures (adverse effects)
  • Radiography
  • Time Factors
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: