A comparison of intralesional triamcinolone acetonide injection for primary chalazion in children and adults.

Abstract

PURPOSE:

To investigate outcome differences of intralesional triamcinolone acetonide (TA) injection for primary chalazia in children versus adults.

METHODS:

A retrospective review of consecutive subjects with primary chalazion who received intralesional TA injection was conducted. A single investigator injected 0.05-0.15 mL of TA (40 mg/mL) intralesionally. Patients were stratified into the pediatric (<18 years old) and adult (≥ 18 years old) group. In both groups, the correlation of resolution time with chalazion size and TA dose was performed.

RESULTS:

17 children and 24 adults were enrolled, with a mean age of 7.4 ± 5.5 and 39.3 ± 16.7 years, respectively. Both groups had statistically similar baseline characteristics. There was no significant difference between the resolution time in the pediatric (18.2 ± 11.4 days) and adult (16.5 ± 11.0 days) group (P = 0.7). There were no significant complications from the TA injection. There was no significant correlation of resolution time to chalazion size (P = 0.7) nor TA dose (P = 0.3) in both groups.

CONCLUSION:

TA for the treatment of primary chalazion was equally effective in children and adults, without any significant complications, and the rate of clinical response did not appear to be dose-dependent.

• Authors: Jacky W Y Lee, Gordon S K Yau, Michelle Y Y Wong, Can Y F Yuen
• Journal: TheScientificWorldJournal (ScientificWorldJournal) Vol. 2014 Pg. 413729 ( 2014) ISSN: 1537-744X [Electronic] United States
• PMID: 25386597 (Publication Type: Journal Article)

Chemical References

• Glucocorticoids
• Triamcinolone Acetonide

Topics

• Administration, Topical
• Adolescent
• Adult
• Chalazion (drug therapy, pathology)
• Child
• Child, Preschool
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Male
• Middle Aged
• Retrospective Studies
• Treatment Outcome
• Triamcinolone Acetonide (administration & dosage)