Exercise-induced rhabdomyolysis.

Abstract

Exercise-induced rhabdomyolysis, or exertional rhabdomyolysis (ER), is a clinical entity typically considered when someone presents with muscle stiffness, swelling, and pain out of proportion to the expected fatigue post exercise. The diagnosis is confirmed by myoglobinuria, and an elevated serum Creatinine Phosphokinase (CPK) level, usually 10 times the normal range. However, an elevation in CPK is seen in most forms of strenuous exercise, up to 20 times the upper normal range. Therefore, there is no definitive pathologic CPK cut-off. Fortunately the dreaded complication of acute renal failure is rare compared to other forms rhabdomyolysis. We review the risks, diagnosis, clinical course and treatment for exercise- induced rhabdomyolysis.

• Authors: George Lee
• Journal: Rhode Island medical journal (2013) (R I Med J (2013)) Vol. 97 Issue 11 Pg. 22-4 (Nov 03 2014) ISSN: 2327-2228 [Electronic] United States
• PMID: 25365815 (Publication Type: Journal Article, Review)

Chemical References

• Creatine Kinase

Topics

• Acute Kidney Injury (therapy)
• Creatine Kinase (blood)
• Exercise
• Humans
• Myoglobinuria (urine)
• Rhabdomyolysis (complications, diagnosis, therapy)
• Risk Factors