Abstract | INTRODUCTION:
Methoxphenidine is a novel dissociative designer drug of the diarylethylamine class which shares structural features with phencyclidine (PCP), and is not at present subject to restrictive regulations. There is very limited information about the acute toxicity profile of methoxphenidine and the only sources are anonymous internet sites and a 1989 patent of the Searle Company. We report a case of analytically confirmed oral methoxphenidine toxicity. CASE DETAILS: CONCLUSION: Based on this case report and users' web reports, and compatible with the chemical structure, methoxphenidine produces effects similar to those of the arylcyclohexylamines, as PCP.
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Authors | Katharina E Hofer, Colette Degrandi, Daniel M Müller, Ursina Zürrer-Härdi, Schirin Wahl, Christine Rauber-Lüthy, Alessandro Ceschi |
Journal | Clinical toxicology (Philadelphia, Pa.)
(Clin Toxicol (Phila))
Vol. 52
Issue 10
Pg. 1288-91
(Dec 2014)
ISSN: 1556-9519 [Electronic] England |
PMID | 25350467
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Biomarkers
- Illicit Drugs
- Piperidines
- Psychotropic Drugs
- 1-(1-(2-methoxyphenyl)-2-phenylethyl)piperidine
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Topics |
- Biomarkers
(blood, urine)
- Biotransformation
- Cardiovascular Diseases
(chemically induced, diagnosis, physiopathology, therapy)
- Cardiovascular System
(drug effects, physiopathology)
- Chromatography, Liquid
- Confusion
(chemically induced, diagnosis, physiopathology)
- Humans
- Illicit Drugs
(blood, pharmacokinetics, poisoning, urine)
- Male
- Middle Aged
- Nervous System
(drug effects, physiopathology)
- Neurotoxicity Syndromes
(diagnosis, etiology, physiopathology, therapy)
- Piperidines
(blood, pharmacokinetics, poisoning, urine)
- Psychotropic Drugs
(blood, pharmacokinetics, poisoning, urine)
- Substance-Related Disorders
(complications)
- Tandem Mass Spectrometry
- Treatment Outcome
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