HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Clinical evaluation of josamycin in the treatment of acne].

Abstract
The efficacy of josamycin in the treatment of inflammatory acne has been evaluated in 39 patients. Josamycin was orally administered to the patients as a single 500 mg daily dose for two months, but the patients with the most severe lesions received an initial treatment of 1 g for a maximum of 20 days. All subjects received josamycin in combination with other antiacne drugs mostly benzoyl peroxide ointment. The treatment induced a significant regression of the number and the severity of the lesions scored according to Plewig-Kligman's classification. At the end of the treatment a positive effect was observed for 92% of the subjects, independently of the variety and the degree of the severity of the disease. According to the patients' judgments josamycin was an effective treatment (92.3%) and more effective that the previously prescribed drugs (95%). Only 1 patient reported the occurrence of a side effect (mild gastric discomfort). Josamycin showed in this study to be an effective and safe drug for the treatment of inflammatory acne.
AuthorsS Bundino, R Salomone, A M Zina
JournalGiornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (G Ital Dermatol Venereol) 1989 Nov-Dec Vol. 124 Issue 11-12 Pg. LV-LX ISSN: 0392-0488 [Print] Italy
Vernacular TitleValutazione clinica della josamicina nella terapia dell'acne.
PMID2534716 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Josamycin
Topics
  • Acne Vulgaris (drug therapy)
  • Adolescent
  • Adult
  • Drug Administration Schedule
  • Drug Evaluation
  • Female
  • Humans
  • Josamycin (administration & dosage, therapeutic use)
  • Male

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: