A 4% erythromycin and zinc combination (Zineryt) versus 2% erythromycin (Eryderm) in acne vulgaris: a randomized, double-blind comparative study.

Abstract

A double-blind, randomized multi-centre study was performed to evaluate the efficacy of a 4% erythromycin and zinc combination (Zineryt) versus 2% erythromycin (Eryderm). One-hundred and twenty-two patients suffering from acne vulgaris were treated with either Zineryt lotion or 2% erythromycin lotion. Acne grading and lesion counts for comedones, papules, pustules, nodules and macules were performed at each visit at 0, 1, 2, 4, 8 and 12 weeks. Treatment with Zineryt lotion was found to be more effective than with 2% erythromycin as regards the reduction in number of the acne lesions and the severity grade of the acne.

• Authors: L Habbema, B Koopmans, H E Menke, S Doornweerd, K De Boulle
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 121 Issue 4 Pg. 497-502 (Oct 1989) ISSN: 0007-0963 [Print] England
• PMID: 2533878 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)

Chemical References

• Acetates
• Drug Combinations
• Erythromycin
• Acetic Acid

Topics

• Acetates (therapeutic use)
• Acetic Acid
• Acne Vulgaris (drug therapy)
• Adolescent
• Adult
• Double-Blind Method
• Drug Combinations
• Erythromycin (therapeutic use)
• Humans
• Multicenter Studies as Topic
• Randomized Controlled Trials as Topic