Abstract | PURPOSE: Although penile duplex Doppler ultrasonography (PDDU) is a common and integral procedure in a Peyronie's disease workup, the intracavernosal injection of vasoactive agents can carry a serious risk of priapism. Risk factors include young age, good baseline erectile function, and no coronary artery disease. In addition, patients with Peyronie's disease undergoing PDDU in an outpatient setting are at increased risk given the inability to predict optimal dosing. The present study was conducted to provide support for a standard protocol of early administration of phenylephrine in patients with a sustained erection after diagnostic intracavernosal injection of vasoactive agents to prevent the deleterious effects of iatrogenic priapism. MATERIALS AND METHODS: RESULTS: CONCLUSIONS:
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Authors | Pengbo Jiang, Athena Christakos, Mina Fam, Hossein Sadeghi-Nejad |
Journal | Korean journal of urology
(Korean J Urol)
Vol. 55
Issue 10
Pg. 665-9
(Oct 2014)
ISSN: 2005-6745 [Electronic] Korea (South) |
PMID | 25324950
(Publication Type: Journal Article, Review)
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Chemical References |
- Vasoconstrictor Agents
- Vasodilator Agents
- Phenylephrine
- Alprostadil
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Topics |
- Alprostadil
(adverse effects)
- Drug Evaluation
(methods)
- Humans
- Male
- Middle Aged
- Penile Erection
- Penile Induration
(diagnostic imaging)
- Phenylephrine
(therapeutic use)
- Pilot Projects
- Priapism
(chemically induced, prevention & control)
- Retrospective Studies
- Ultrasonography, Doppler, Duplex
(adverse effects, methods)
- Vasoconstrictor Agents
(therapeutic use)
- Vasodilator Agents
(adverse effects)
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