A cross-sectional study on urogenital schistosomiasis in children; haematuria and proteinuria as diagnostic indicators in an endemic rural area of Nigeria.

Abstract

BACKGROUND:

Rapid and accurate diagnosis is necessary for the management of schistosomiasis in endemic areas.

OBJECTIVE:

To assess the burden of urogenital schistosomiasis and the diagnostic efficiency of morbidity indicators of the disease in an endemic rural community of Nigeria.

METHODS:

A cross-sectional school-based study was conducted. Urine samples of 487 pupils were screened microscopically for S. haematobium and tested for haematuria and proteinuria using chemical reagent strips.

RESULTS:

The prevalence and intensity of infection were 57.1% and 45.0 eggs/10 mL urine respectively. Prevalence of infection in male (54.1%) and female (60.3%) individuals showed no significant variation (P>0.05). However, prevalence of infection was age dependent with those in age groups 3-5 and 12-14 years having the least and highest prevalence of infection respectively (P<0.05). Microhaematuria and proteinuria varied significantly with ages of the pupils with least (14.0, 40.0%) and highest (60.0, 80.0%) prevalence recorded in age groups 3-5 and 15-19 years respectively (P<0.05). Proteinuria showed higher sensitivity (80.3%) compared to microhaematuria (73.3%).

CONCLUSION:

Schistosomiasis is highly endemic in the study area and the use of microhaematuria and proteinuria for mapping the infected population prior treatment could be adopted.

• Authors: Olajumoke Morenikeji, Junaid Quazim, Claire Omoregie, Adesola Hassan, Roseangela Nwuba, Chiaka Anumudu, Sunday Adejuwon, Oyetunde Salawu, Ayodele Jegede, Alexander Odaibo
• Journal: African health sciences (Afr Health Sci) Vol. 14 Issue 2 Pg. 390-6 (Jun 2014) ISSN: 1729-0503 [Electronic] Uganda
• PMID: 25320589 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Child
• Child, Preschool
• Cross-Sectional Studies
• Female
• Hematuria (parasitology, urine)
• Humans
• Male
• Morbidity
• Nigeria (epidemiology)
• Prevalence
• Proteinuria (parasitology, urine)
• Rural Population
• Schistosomiasis haematobia (diagnosis, epidemiology, urine)
• Schools
• Severity of Illness Index