HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Reduction of CT beam hardening artefacts of ethylene vinyl alcohol copolymer by variation of the tantalum content: evaluation in a standardized aortic endoleak phantom.

AbstractOBJECTIVES:
Our aim was to develop an aortic stent graft phantom to simulate endoleak treatment and to find a tantalum content (TC) of ethylene-vinyl-alcohol-copolymer that causes fewer computed tomography (CT) beam hardening artefacts, but still allows for fluoroscopic visualization.
METHODS:
Ethylene-vinyl-alcohol-copolymer specimens of different TC (10-50 %, and 100 %) were injected in an aortic phantom bearing a stent graft and endoleak cavities with simulated re-perfusion. Fluoroscopic visibility of the ethylene-vinyl-alcohol-copolymer specimens was analyzed. In addition, six radiologists analyzed endoleak visibility, and artefact intensity of ethylene-vinyl-alcohol-copolymer in CT.
RESULTS:
Reduction of TC significantly decreased CT artefact intensity of ethylene-vinyl-alcohol-copolymer and increased visibility of endoleak re-perfusion (p < 0.000). It also significantly decreased fluoroscopic visibility of ethylene-vinyl-alcohol-copolymer (R = 0.883, p ≤ 0.01), and increased the active embolic volumes prior to visualization (Δ ≥ 40 μl). Ethylene-vinyl-alcohol-copolymer specimens with a TC of 45-50 % exhibited reasonable visibility, a low active embolic volume and a tolerable CT artefact intensity.
CONCLUSIONS:
The developed aortic stent graft phantom allows for a reproducible simulation of embolization of endoleaks. The data suggest a reduction of the TC of ethylene-vinyl-alcohol-copolymer to 45 -50 % of the original, to interfere less with diagnostic imaging in follow-up CT examinations, while still allowing for fluoroscopic visualization.
AuthorsKarla M Treitl, Michael Scherr, Monika Förth, Franziska Braun, Daniel Maxien, Marcus Treitl
JournalEuropean radiology (Eur Radiol) Vol. 25 Issue 3 Pg. 597-605 (Mar 2015) ISSN: 1432-1084 [Electronic] Germany
PMID25319348 (Publication Type: Evaluation Studies, Journal Article)
Chemical References
  • Polyvinyls
  • ethylene-vinyl alcohol copolymer
  • Tantalum
Topics
  • Aortic Aneurysm, Abdominal (radiography)
  • Artifacts
  • Embolization, Therapeutic (methods)
  • Endoleak (radiography)
  • Fluoroscopy
  • Humans
  • Phantoms, Imaging
  • Polyvinyls (chemistry)
  • Stents
  • Tantalum (chemistry)
  • Tomography, X-Ray Computed (instrumentation, methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: