Treatment of acute salpingitis with sulbactam/ampicillin.

Abstract

The combination of sulbactam/ampicillin was compared to cefoxitin for the treatment of acute salpingitis in 40 women divided into two groups of 20 women each. There were 11 patients in each group who were given doxycycline because of evidence of chlamydial infection. All patients were diagnosed by laparoscopic examination and evaluated by the same procedure 7-12 weeks later. At the second laparoscopy, only 1 of the 20 patients (5%) treated with sulbactam/ampicillin had severe adhesions, while 6 of the 20 patients (40%) treated with cefoxitin had severe adhesions. Tubal patency was without obstruction in 14 patients (70%) given the combination treatment and in 12 patients (60%) given cefoxitin. Side effects were essentially absent in both groups.

• Authors: M A Bruhat, G LeBouedec, J L Pouly, G Mage, M Canis
• Journal: Supplement to International journal of gynecology and obstetrics (Suppl Int J Gynecol Obstet) Vol. 2 Pg. 41-6; discussion 47-8 ( 1989) ISSN: 0924-8447 [Print] Ireland
• PMID: 2529873 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Ampicillin
• Sulbactam

Topics

• Acute Disease
• Adult
• Ampicillin (adverse effects, therapeutic use)
• Drug Therapy, Combination (adverse effects, therapeutic use)
• Female
• Humans
• Laparoscopy
• Randomized Controlled Trials as Topic
• Salpingitis (drug therapy, microbiology, physiopathology)
• Sulbactam (adverse effects, therapeutic use)