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[Eosinophilic fasciitis, morphea and vitiligo in a single patient].

AbstractBACKGROUND:
Fasciitis with eosinophilia (FE), or Shulman syndrome, is a rare disease of unknown origin for which the nosological profile has not been clearly defined. It is clinically characterised by oedema and induration of the limbs with hypereosinophilia. It may be associated with morphea, in which case it carries a poor prognosis, or other diseases, particularly autoimmune conditions. Herein, we report a case of fasciitis associated with eosinophilia, morphea and vitiligo.
PATIENT AND METHODS:
A 45-year-old male patient followed up for vitiligo for 20 years had been presenting swelling and induration of the skin on all 4 limbs for the previous 7 months associated with morphea on the trunk. Treatment consisting of systemic corticosteroids and methotrexate was initiated and displayed a certain degree of efficacy.
DISCUSSION:
The association of morphea/fasciitis with eosinophilia is a classical finding; the presence of vitiligo raises the question of possible association between these different disorders.
AuthorsS Lakjiri, M Meziane, A Benani, T Harmouch, A Amarti, F-Z Mernissi
JournalAnnales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 141 Issue 10 Pg. 598-602 (Oct 2014) ISSN: 0151-9638 [Print] France
Vernacular TitleAssociation fasciite avec éosinophilie, morphées et vitiligo.
PMID25288063 (Publication Type: Case Reports, English Abstract, Journal Article)
CopyrightCopyright © 2014 Elsevier Masson SAS. All rights reserved.
Topics
  • Biopsy
  • Diagnosis, Differential
  • Eosinophilia (complications, diagnosis, pathology)
  • Fascia (pathology)
  • Fasciitis (complications, diagnosis, pathology)
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Muscle, Skeletal (pathology)
  • Scleroderma, Localized (complications, diagnosis, pathology)
  • Skin (pathology)
  • Synovitis (complications, diagnosis, pathology)
  • Vitiligo (complications, diagnosis, pathology)

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