Evaluation of pemphigus cases involving oral mucosa.

Abstract

PURPOSE:

Pemphigus, defines a group of disorders in autoimmune etiology which could be life-threatening and clinical manifestations are mainly epithelial blistering affecting cutaneous and/or mucosal surfaces including oral mucosa. The aim of our study is to evaluate the clinical appearance of pemphigus with oral involvement by reported 15 pemphigus cases.

MATERIAL AND METHODS:

This retrospective study of 15 cases of pemphigus obtained over a period of 7 years from 2006 to 2013 in Istanbul University, Dentistry Faculty, Oral Medicine and Surgery Department was designed.

RESULTS:

Age distribution of pemphigus was from 15 to 59 years with an average age of 41.3 years. Of the 15 patients, the male:female ratio was 1:2.75 (4 male, 11 female). The most common clinical various of pemphigus was pemphigus vulgaris, diagnosed in all patients. The buccal mucosa (34.3%) was the most commonly affected site followed by tongue (20%), gingiva (17.1%), palate (11.4%), lips (11.4%) and floor of mouth (5.7%).

CONCLUSION:

Our explanation of this conclusion, while speculative, is that socioeconomic situation related stress in males and hormonal changes like pregnancy and menostasis in females; systemic disease and using drugs; dental trauma and bruxism could be responsible for flare up in the disease.

• Authors: Gizem Karagöz, Kivanç Bektaş-Kayhan, Meral Ünür
• Journal: Oral health and dental management (Oral Health Dent Manag) Vol. 13 Issue 3 Pg. 605-9 (Sep 2014) ISSN: 2247-2452 [Print] United States
• PMID: 25284520 (Publication Type: Journal Article)