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[QT Variability Index as a tool for risk stratification of sudden cardiac death].

Abstract
Sudden cardiac death is the leading cause of mortality in patients with chronic heart failure (CHF) and history of myocardial infarction. Selection of patients at risk of sudden cardiac death is dramatically important to choose the correct therapeutic approach. The QT Variability Index (QTVI) is a non-invasive measure of repolarization lability that has been applied to a wide variety of subjects with cardiovascular disease. It is a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of the autonomic nervous system tone. As opposed to T wave alternans, QTVI assesses variance in repolarization at all frequencies. Recent studies suggest that QTVI may help clinicians choosing the appropriate implantable cardiovester defibrillator timing implantation, in patients with dilated or hypertrophic cardiomyopathy or CHF because of its efficacy in patient evaluation and follow-up.
AuthorsGianfranco Piccirillo, Federica Moscucci, Damiano Magrì
JournalRecenti progressi in medicina (Recenti Prog Med) Vol. 105 Issue 10 Pg. 385-91 (Oct 2014) ISSN: 0034-1193 [Print] Italy
Vernacular TitleIl QT Variability Index come strumento per la stratificazione del rischio di morte improvvisa.
PMID25282351 (Publication Type: English Abstract, Journal Article)
Topics
  • Autonomic Nervous System (physiopathology)
  • Cardiovascular Diseases (physiopathology)
  • Death, Sudden, Cardiac (etiology, prevention & control)
  • Electrocardiography
  • Heart Failure (complications, mortality)
  • Heart Rate (physiology)
  • Humans
  • Myocardial Infarction (complications, mortality)
  • Risk Assessment (methods)

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