Congestive Heart Failure With Apparently Preserved Left Ventricular Systolic Function: A 10-Year Observational Study.

Abstract

We analyzed the clinical presentation and outcomes (from 2003 to 2013) of heart failure (HF) with apparently normal systolic function (HFPEF). Based on the echocardiographic left ventricular ejection fraction (LVEF), patients were divided into 2 groups, group 1 (<50%) and group 2 (≥50%). Of 2212 patients with HF, 20% were in group 2. Patients in group 2 were more likely to be older, females, Arabs, hypertensive, and obese (P = .001). Patients in group 1 were mostly Asians and had more troponin-T positivity (P = .001). Inhospital cardiac arrest, shock, and deaths were significantly greater in group 1. On multivariate analysis, age, ST-segment elevation myocardial infarction, lack of on-admission β-blockers, and angiotensin-converting enzyme inhibitors use were independent predictors of mortality. HFPEF is associated with less mortality compared to those who presented with reduced LVEF. On admission, use of evidence-based medications could in part predict this difference in the hospital outcome.

• Authors: Ayman El-Menyar, Adel Shabana, Abdulrahman Arabi, Hassan Al-Thani, Nidal Asaad, Hajar AlBinALi, Rajvir Singh, Mohammed Gomaa, A Gehani
• Journal: Angiology (Angiology) Vol. 66 Issue 8 Pg. 738-44 (Sep 2015) ISSN: 1940-1574 [Electronic] United States
• PMID: 25248442 (Publication Type: Comparative Study, Journal Article, Observational Study)
• Copyright: © The Author(s) 2014.

Chemical References

• Biomarkers
• Cardiovascular Agents
• Troponin T

Topics

• Age Factors
• Aged
• Biomarkers (blood)
• Cardiovascular Agents (therapeutic use)
• Comorbidity
• Female
• Heart Failure (blood, diagnosis, drug therapy, ethnology, mortality, physiopathology)
• Hospital Mortality
• Hospitalization
• Humans
• Incidence
• Male
• Middle Aged
• Prevalence
• Prognosis
• Qatar (epidemiology)
• Racial Groups
• Retrospective Studies
• Risk Factors
• Stroke Volume
• Systole
• Time Factors
• Troponin T (blood)
• Ventricular Function, Left