Abstract | OBJECTIVE: METHODS: Data on benefits of deep brain electrical stimulation come from a recent review. Stimulated brain regions included subgenual cingulate, capsular interna, nucleus accumbens, and medial forebrain bundle. Expert opinion plus random number software was used to generate hypothetical values for sham responding. RESULTS: CONCLUSION: Preliminary findings on deep brain electrical stimulation suggest that the procedure may be 71% more effective than sham treatment. Expressing these findings as patients-needed-to-treat, deep brain electrical stimulation is required by 2.9 patients with long-term treatment-resistant depression in order for one of them to benefit.
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Authors | Donald F Smith |
Journal | Acta neuropsychiatrica
(Acta Neuropsychiatr)
Vol. 26
Issue 6
Pg. 382-4
(Dec 2014)
ISSN: 1601-5215 [Electronic] England |
PMID | 25231031
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
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Topics |
- Deep Brain Stimulation
- Depressive Disorder, Treatment-Resistant
(therapy)
- Humans
- Placebos
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