Abstract | BACKGROUND:
Thalassemia major is one of the most common genetic disorders in Pakistan and over five thousand new patients are added in the pool annually. This familial disease has both medical and social implications, and therefore there is a need to assess the magnitude of beta-Thalassemia trait amongst family members of Thalassemia major patients. METHODS: This cross-sectional descriptive study enrolled 674 blood samples from first degree relatives of registered patients of Thalassemia major at Sir Ganga Ram Hospital, Lahore. Peripheral blood smears were studied for abnormal morphology findings of microcytosis, hypochromia, poikilocytosis (tear drops, target cells) and Erythrocyte indices (haemoglobin, RBCs, mean corpuscular haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin concentration) and Hb electrophoretic (HbA, HbA2, & HbF). RESULTS: CONCLUSION:
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Authors | Tazeen Majeed, Mohammed Adil Akhter, Ujala Nayyar, Muhammad Safwan Riaz, Jovaria Mannan |
Journal | Journal of Ayub Medical College, Abbottabad : JAMC
(J Ayub Med Coll Abbottabad)
2013 Jul-Dec
Vol. 25
Issue 3-4
Pg. 58-60
ISSN: 1025-9589 [Print] Pakistan |
PMID | 25226742
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Cross-Sectional Studies
- Electrophoresis
- Erythrocyte Indices
- Female
- Hemoglobins
(analysis, chemistry, classification, isolation & purification)
- Humans
- Infant
- Male
- Middle Aged
- Pakistan
(epidemiology)
- Young Adult
- beta-Thalassemia
(blood, epidemiology)
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