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Comparison of 3 silicone hydrogel bandage soft contact lenses for pain control after photorefractive keratectomy.

AbstractPURPOSE:
To evaluate the relative pain with 3 U.S. Food and Drug Administration-approved bandage soft contact lenses (SCLs) applied after photorefractive keratectomy (PRK).
SETTING:
Joint Warfighter Refractive Surgery Center, Lackland Air Force Base, Texas, USA.
DESIGN:
Prospective comparative case series.
METHODS:
Patients having PRK were randomized to a senofilcon A (Acuvue Oasys), balafilcon A (Purevision), or lotrafilcon A (Air Optix) bandage SCL in each eye postoperatively. Patients were evaluated 1 and 4 days postoperatively and completed a survey rating absolute pain in each eye on a visual analog scale.
RESULTS:
The study enrolled 54 patients. At 1 and 4 days, eyes with the senofilcon A lens had the lowest pain scores followed by eyes with the lotrafilcon A lens and then eyes with the balafilcon A lens. Averaging qualitative results from 1 and 4 days showed that eyes with the senofilcon A lens were reported as having more pain by 4% of patients, eyes with the lotrafilcon A lens by 27%, and eyes with the balafilcon A lens by 53%; 16% reported no difference (P<.001). Quantitatively, the senofilcon A lens was 40% more comfortable than the lotrafilcon A lens and 65% more comfortable than the balafilcon A lens on average. The lotrafilcon A lens was 38% more comfortable than the balafilcon A lens on average (P<.01).
CONCLUSIONS:
There was a statistically and clinically significant difference in post-PRK pain between the 3 bandage SCLs. The senofilcon A lens caused the least pain.
FINANCIAL DISCLOSURE:
Dr. Reilly is a consultant to Alcon Laboratories, Inc. and Abbott Medical Optics, Inc. but was not at the time of the study. No other author has a financial or proprietary interest in any material or method mentioned.
AuthorsKenneth R Taylor, Matthew C Caldwell, Angeletta M Payne, Douglas A Apsey, J Richard Townley, Charles D Reilly, Vasudha A Panday
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 40 Issue 11 Pg. 1798-804 (Nov 2014) ISSN: 1873-4502 [Electronic] United States
PMID25217073 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
CopyrightPublished by Elsevier Inc.
Chemical References
  • Silicones
Topics
  • Adult
  • Bandages, Hydrocolloid
  • Contact Lenses, Hydrophilic
  • Eye Pain (therapy)
  • Female
  • Health Surveys
  • Humans
  • Male
  • Pain Measurement
  • Pain, Postoperative (therapy)
  • Patient Satisfaction
  • Photorefractive Keratectomy
  • Prospective Studies
  • Silicones
  • Surveys and Questionnaires

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