A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration.

Abstract

BACKGROUND:

To evaluate the potential of lowering intraocular pressure in pseudoexfoliation glaucoma with combined phacoemulsification, Trabectome, and trabecular aspiration (triple procedure) compared to phacoemulsification and trabecular aspiration alone.

METHODS:

Using a case-matched retrospective study design, 30 patients were included into each group. The main outcome measures were the reduction of intraocular pressure and medication score at the end of follow-up. Clinical data were collected from the patients' medical records.

RESULTS:

Mean follow-up was 15 months in both groups. Intraocular pressure decreased from 25.3 ± 6.3 mmHg to 14.4 ± 3.7 mmHg (p < 0.0001) in the triple procedure group and from 25.3 ± 4.2 mmHg to 18.1 ± 4.2 mmHg (p < 0.0001) in the control group. The medication score was lowered from 3.4 ± 1.7 to 2.1 ± 1.2 (p = 0.0017) in the triple procedure group and from 3.8 ± 1.8 to 2.3 ± 1.5 (p < 0.008) in the control group. The reduction of intraocular pressure was higher (p < 0.004) in the triple procedure group (38.4 ± 17.3 %) compared to the control group (26.8 ± 19.6 %) The reduction of the medication score did not differ significantly.

CONCLUSIONS:

The triple procedure is more effective in lowering intraocular pressure compared to phacoemulsification and trabecular aspiration alone in pseudoexfoliation glaucoma.

• Authors: Randolf A Widder, Sven Dinslage, André Rosentreter, Jens F Jordan, Pia Kühnrich, Claus Cursiefen, Klaus-Dieter Lemmen, Thomas S Dietlein
• Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (Graefes Arch Clin Exp Ophthalmol) Vol. 252 Issue 12 Pg. 1971-5 (Dec 2014) ISSN: 1435-702X [Electronic] Germany
• PMID: 25212496 (Publication Type: Journal Article)

Topics

• Aged
• Aged, 80 and over
• Drainage (methods)
• Exfoliation Syndrome (physiopathology, surgery)
• Female
• Follow-Up Studies
• Glaucoma, Open-Angle (physiopathology, surgery)
• Humans
• Intraocular Pressure (physiology)
• Male
• Middle Aged
• Phacoemulsification (methods)
• Retrospective Studies
• Tonometry, Ocular
• Trabeculectomy (methods)