[Treatment of keloid with phenol: a new therapy].

Abstract

PURPOSE:

Evaluation of a new treatment for keloid scars using a 40% phenol solution in accordance with a predefined protocol.

PATIENTS AND METHODS:

A retrospective study was made of the files of 25 patients treated with phenol from June 2010 to March 2012.

RESULTS:

The keloids were located predominantly on the trunk (48%) and upper extremities (34%). The total number of keloids was 52, with a median size of 11.16 cm(2). Phenol was the sole and first-line treatment in 40% of cases. Patient adherence to the protocol of phenol was noted in 81% of cases. The mean number of phenol sessions was 14.2. Seventy-two percent of patients were satisfied with the treatment. Mean regression in keloid size of 75.5% was noted. A change in local keloid pigmentation was observed in 75% of patients. Local adverse reactions (itching, infection, ulceration) were seen in 6 patients (28.6%). No cases of systemic signs of phenol were observed. After mean follow-up of 12.8 months, no recurrence of keloids was noted.

CONCLUSION:

Use of phenols in the topical treatment of keloids appears valuable since it is easy to apply and provides good results with few side effects.

• Authors: M Mseddi, H Mesrati, S Ktaari, M Amouri, H Chaaben, S Boudaya, H Turki
• Journal: Annales de dermatologie et de venereologie (Ann Dermatol Venereol) 2014 Aug-Sep Vol. 141 Issue 8-9 Pg. 493-9 ISSN: 0151-9638 [Print] France
• Vernacular Title: La phénolisation: un nouveau traitement des chéloïdes.
• PMID: 25209811 (Publication Type: Evaluation Study, Journal Article)
• Copyright: Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Chemical References

• Phenol

Topics

• Adolescent
• Adult
• Aged
• Female
• Humans
• Keloid (therapy)
• Male
• Middle Aged
• Phenol (therapeutic use)
• Prospective Studies
• Retrospective Studies
• Young Adult