Abstract | BACKGROUND: Basal cell carcinoma (BCC) recurrences, especially in the facial region, represent a complex cosmetic problem. To date the possibility of predicting recurrence is supported solely by the histologic subtype. OBJECTIVE: To evaluate the relationship between BCC histologic subtypes linked to high and low risk of recurrence and the presence of hyperechoic spots on sonography. METHODS: Retrospective analysis of the pre-surgical ultrasound examinations of primary BCC tumours with visualization and counting of intra-tumoural hyperechoic spots. The data were then correlated with the corresponding histologic subtype. RESULTS: Thirty one patients with histologically proven BCC were included in the study. Hyperechoic spots were detected in all cases and there was a positive, statistically significant association between hyperechoic spots count and high recurrence risk histologic subtypes. Higher hyperechoic spots count was found in the recurrence-prone micronodular, sclerosing variant and morpheiform BCC subtypes. Low risk and high risk of recurrence showed a significant difference on the mean hyperechoic spots count of 5.5 (range: 3-25) and 8 (4-81). A cut-off point ≥7 hyperechoic spots presented a sensitivity of 79% and specificity of 53% for predicting the high risk of recurrence subtypes. CONCLUSION: The presence and count of hyperechoic spots within BCC lesions may help predicting the high risk of recurrence histologic subtypes.
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Authors | X Wortsman, P Vergara, A Castro, D Saavedra, F Bobadilla, I Sazunic, V Zemelman, J Wortsman |
Journal | Journal of the European Academy of Dermatology and Venereology : JEADV
(J Eur Acad Dermatol Venereol)
Vol. 29
Issue 4
Pg. 702-7
(Apr 2015)
ISSN: 1468-3083 [Electronic] England |
PMID | 25200424
(Publication Type: Journal Article)
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Copyright | © 2014 European Academy of Dermatology and Venereology. |
Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Basal Cell
(diagnostic imaging, pathology)
- Facial Neoplasms
(diagnostic imaging, pathology)
- Female
- Head and Neck Neoplasms
(diagnostic imaging, pathology)
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local
- Predictive Value of Tests
- Retrospective Studies
- Risk Factors
- Scalp
- Skin Neoplasms
(diagnostic imaging, pathology)
- Ultrasonography
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