Abstract |
One of the properties often attributed to heterochromatin is its susceptibility to induced aberrations and exchanges. However, earlier studies made mostly on different mammalian in vitro cell lines on the distribution of aberrations within euchromatin and heterochromatin at metaphase chromosome level have given contradictory results. In the present study, an attempt has been made to evaluate the clastogenic sensitivity of heterochromatin and euchromatin using somatic chromosome complements of a submammalian vertebrate as experimental model and considering both chromosome aberrations and SCEs as end points.
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Authors | S N Banerjee, S Chakrabarti |
Journal | In vivo (Athens, Greece)
(In Vivo)
1989 Jan-Feb
Vol. 3
Issue 1
Pg. 55-60
ISSN: 0258-851X [Print] Greece |
PMID | 2519833
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Chromatin
- Heterochromatin
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Topics |
- Animals
- Bone Marrow Cells
- Bufonidae
- Chromatin
(physiology, radiation effects, ultrastructure)
- Chromosome Aberrations
- Chromosome Banding
- Chromosome Mapping
- Female
- Heterochromatin
(physiology, radiation effects, ultrastructure)
- Karyotyping
- Male
- Metaphase
- Mutagenesis
- Whole-Body Irradiation
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