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Effects of high-frequency bio-oxidative ozone therapy in temporomandibular disorder-related pain.

AbstractOBJECTIVE:
It was the aim of this study to compare the efficacy of ozone therapy and drug treatment in patients with painful temporomandibular joint (TMJ) disorder (TMD).
SUBJECTS AND METHODS:
A total of 63 patients with TMD were enrolled; 33 were treated with bio-oxidative therapy and 30 with a ketoprofen tablet thiocolchicoside capsule 2 × 1 for 7 days. Maximum voluntary interincisal mouth opening (MMO) was measured in millimeters using a scale and recorded during the pre- and posttreatment periods. The patients evaluated their subjective pain using a visual analogue scale (VAS). Data were analyzed using the Mann-Whitney U test, the Kolmogorov-Smirnov test, and the independent t test.
RESULTS:
The mean MMO of the group that received ozone therapy during the pretreatment period was 46.51 ± 8.2 mm, and it immediately increased to 48.78 ± 7.5 mm after 1 week of ozone therapy, which was statistically significant (p = 0.04). For those who received medication, the mean MMO during the pretreatment period was 46.30 mm, and at the end of 1 week it was 46.9 mm. In the ozone group, 29% of patients showed a gradual decrease in their VAS pain scores compared to pretreatment values (6.3 ± 2.1 to 3.0 ± 2.2). In the medication group, 24% of patients showed a significant decrease in VAS pain scores during the follow-up period (6.9 ± 1.4 to 5.0 ± 1.5).
CONCLUSION:
This study showed that bio-oxidative therapy was a more effective treatment than medication therapy for relieving TMJ pain.
AuthorsMansur Doğan, Derya Ozdemir Doğan, Cevdet Düger, Iclal Ozdemir Kol, Aysun Akpınar, Burcu Mutaf, Türker Akar
JournalMedical principles and practice : international journal of the Kuwait University, Health Science Centre (Med Princ Pract) Vol. 23 Issue 6 Pg. 507-10 ( 2014) ISSN: 1423-0151 [Electronic] Switzerland
PMID25196631 (Publication Type: Journal Article, Randomized Controlled Trial)
Copyright© 2014 S. Karger AG, Basel.
Chemical References
  • Analgesics
  • Ozone
  • Ketoprofen
  • Colchicine
  • thiocolchicoside
Topics
  • Adult
  • Analgesics (administration & dosage)
  • Colchicine (administration & dosage, analogs & derivatives)
  • Female
  • Humans
  • Ketoprofen (administration & dosage)
  • Male
  • Middle Aged
  • Ozone (therapeutic use)
  • Pain Measurement
  • Temporomandibular Joint Disorders (therapy)

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