Abstract | OBJECTIVE: It was the aim of this study to compare the efficacy of ozone therapy and drug treatment in patients with painful temporomandibular joint ( TMJ) disorder (TMD). SUBJECTS AND METHODS: A total of 63 patients with TMD were enrolled; 33 were treated with bio-oxidative therapy and 30 with a ketoprofen tablet thiocolchicoside capsule 2 × 1 for 7 days. Maximum voluntary interincisal mouth opening (MMO) was measured in millimeters using a scale and recorded during the pre- and posttreatment periods. The patients evaluated their subjective pain using a visual analogue scale (VAS). Data were analyzed using the Mann-Whitney U test, the Kolmogorov-Smirnov test, and the independent t test. RESULTS: The mean MMO of the group that received ozone therapy during the pretreatment period was 46.51 ± 8.2 mm, and it immediately increased to 48.78 ± 7.5 mm after 1 week of ozone therapy, which was statistically significant (p = 0.04). For those who received medication, the mean MMO during the pretreatment period was 46.30 mm, and at the end of 1 week it was 46.9 mm. In the ozone group, 29% of patients showed a gradual decrease in their VAS pain scores compared to pretreatment values (6.3 ± 2.1 to 3.0 ± 2.2). In the medication group, 24% of patients showed a significant decrease in VAS pain scores during the follow-up period (6.9 ± 1.4 to 5.0 ± 1.5). CONCLUSION: This study showed that bio-oxidative therapy was a more effective treatment than medication therapy for relieving TMJ pain.
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Authors | Mansur Doğan, Derya Ozdemir Doğan, Cevdet Düger, Iclal Ozdemir Kol, Aysun Akpınar, Burcu Mutaf, Türker Akar |
Journal | Medical principles and practice : international journal of the Kuwait University, Health Science Centre
(Med Princ Pract)
Vol. 23
Issue 6
Pg. 507-10
( 2014)
ISSN: 1423-0151 [Electronic] Switzerland |
PMID | 25196631
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © 2014 S. Karger AG, Basel. |
Chemical References |
- Analgesics
- Ozone
- Ketoprofen
- Colchicine
- thiocolchicoside
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Topics |
- Adult
- Analgesics
(administration & dosage)
- Colchicine
(administration & dosage, analogs & derivatives)
- Female
- Humans
- Ketoprofen
(administration & dosage)
- Male
- Middle Aged
- Ozone
(therapeutic use)
- Pain Measurement
- Temporomandibular Joint Disorders
(therapy)
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