Intradermal botulinum toxin a for peristomal hyperhidrosis: a case study.

Abstract

BACKGROUND:

Peristomal hyperhidrosis can interfere with pouch adherence, resulting in pouch leakage and peristomal skin damage.

CASE:

A patient with autonomic dysregulation resulting in excessive sweating (hyperhidrosis) experienced difficulty with adherence of her ileostomy appliance. Two hundred units of botulinum toxin A (BTX-A) were injected in the dermis of the surrounding skin in order to improve adherence of her pouching system and alleviate moisture of her peristomal skin.

RESULTS:

Following BTX-A injection, the typical wear time of her pouching system improved from less than 24 hours to 120 hours. Peristomal moisture-associated skin damage resolved almost completely. These effects lasted 3 months. A repeat intradermal BTX-A injection had a similar positive effect.

CONCLUSION:

Peristomal hyperhidrosis can be controlled with BTX-A intradermal injections, improving patient pouch adherence and alleviating moisture-associated skin damage.

• Authors: Kristen Kalkbrenner, Kyle Sanniec, Lyndsey Bryant, Jacques Heppell, Heather McEntarffer, Alanna Rebecca
• Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society (J Wound Ostomy Continence Nurs) 2014 Sep-Oct Vol. 41 Issue 5 Pg. 484-6 ISSN: 1528-3976 [Electronic] United States
• PMID: 25188804 (Publication Type: Case Reports, Journal Article)

Chemical References

• DWP450
• Botulinum Toxins, Type A

Topics

• Adult
• Botulinum Toxins, Type A (drug effects, therapeutic use)
• Female
• Humans
• Hyperhidrosis (complications)
• Injections, Intradermal (statistics & numerical data)
• Surgical Stomas (adverse effects)