Abstract | BACKGROUND: METHODS: Demographics, prestroke conditions, poststroke National Institutes of Health Stroke Scale score, and clinical and laboratory parameters were prospectively registered in 216 Taiwanese patients. One hundred forty patients who completed follow-up 3 months after experiencing ischemic stroke were assessed with the modified Rankin scale as functional prognoses. RESULTS: Twenty-one patients used thiazide to control hypertension before experiencing ischemic stroke. No differences of stroke subtypes and comorbidities before stroke were observed between the 2 groups. The emergency department National Institutes of Health Stroke Scale was lesser among thiazide users (4 [2-7] versus 6 [4-16], P = .02). Among 140 patients who completed follow-up in 90 days, thiazide users had more favorable functional status (modified Rankin scale ≤2: 42.4% versus 26.9%, P = .02, odds ratio 3.34, 95%, confidence interval .130-.862). CONCLUSION:
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Authors | Hong-Mo Shih, Wei Chun Lin, Cheng-Hsien Wang, Leng-Chieh Lin |
Journal | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
(J Stroke Cerebrovasc Dis)
Vol. 23
Issue 9
Pg. 2414-8
(Oct 2014)
ISSN: 1532-8511 [Electronic] United States |
PMID | 25183562
(Publication Type: Journal Article, Observational Study, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Brain Ischemia
(physiopathology)
- Diuretics
(therapeutic use)
- Female
- Humans
- Hypertension
(complications, drug therapy)
- Male
- Middle Aged
- Primary Prevention
- Prognosis
- Prospective Studies
- Stroke
(physiopathology, prevention & control)
- Thiazides
(therapeutic use)
- Treatment Outcome
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