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Case report: new treatment with Tolvaptan for heart failure after cardiac surgery.

Abstract
The vasopressin V2 receptor antagonist (Tolvaptan) is a new diuretic that selectively promotes the excretion of water. It has been reported to be effective for patients in cardiology, but there have been no reports of its use in the perioperative period after cardiac surgery. We report the usefulness of Tolvaptan for postoperative fluid management in a patient with severe mitral regurgitation due to ischemic cardiomyopathy. Marked improvement was achieved after administration of Tolvaptan for heart failure in the postoperative period.
AuthorsAkira Sezai, Mitsuru Iida, Isamu Yoshitake, Shunji Osaka, Hiroaki Hata, Motomi Shiono
JournalThe heart surgery forum (Heart Surg Forum) Vol. 17 Issue 4 Pg. E198-200 (Aug 2014) ISSN: 1522-6662 [Electronic] United States
PMID25179972 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Benzazepines
  • Diuretics
  • Tolvaptan
Topics
  • Benzazepines (administration & dosage)
  • Diuretics (administration & dosage)
  • Heart Failure (drug therapy, etiology)
  • Heart Valve Prosthesis Implantation (adverse effects)
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency (complications, surgery)
  • Tolvaptan
  • Treatment Outcome
  • Water-Electrolyte Imbalance (drug therapy, etiology, prevention & control)

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