The present study was designed to explore the existence of oral Helicobacter pylori (H. pylori), its relationship in the oral cavity to the success rate of eradication of the gastric H. pylori
infection, and to determine if the mouthwash
solution contained
lysine (0.4%) and
glycerol monolaurate (0.2%) (LGM) could eliminate oral H. pylori, as well as using the saliva H. pylori culture to confirm the existence of oral H. pylori. A total of 159 symptomatic individuals with stomach
pain and 118 asymptomatic individuals with no stomach complaints, were recruited and tested using the saliva H. pylori
antigen test (HPS), the H. pylori
flagellin test (HPF), the
urea breath test (UBT C(13)) and the polymerase chain reaction (PCR) test, which tests were also confirmed by saliva culture. The test subjects also received various treatments. It was found that the H. pylori
antigen exists in the oral cavity in UBT C(13) negative individuals. Traditional treatment for gastric eradication had only a 10.67 percent (10.67%) effectiveness rate on the oral H. pylori
infection. In groups of patients with the oral H. pylori
infection, but with negative UBT C(13), a mouthwash
solution provided a 72.58% effectiveness rate in the 95% of the confidence interval (CI) ranges on the oral H. pylori
infection. Traditional
drug gastric eradication and teeth cleaning (TC) had less than
a 10% effectiveness rate. Treatment of the oral
infection increased the success rate of eradication of the stomach
infection from 61.33% to 82.26% in the 95% CI ranges. We concluded that the successful rate of eradication of gastric H. pylori bears a significant relationship to the oral
infection from H. pylori.