Serum brain-derived neurotrophic factor (BDNF) and its association with remission status in Chinese patients with schizophrenia.

The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to examine if serum BDNF level is associated with remission status in a sample of Chinese patients with schizophrenia. This study did not find a significant relationship between serum BDNF and remission in patients with schizophrenia. Identification of a suitable biomarker for diagnosis, management, and prognostic outcome is crucial and warrants further study.
AuthorsVidhya Renjan, Milawaty Nurjono, Jimmy Lee
JournalPsychiatry research (Psychiatry Res) Vol. 220 Issue 1-2 Pg. 193-6 (Dec 15 2014) ISSN: 1872-7123 [Electronic] Ireland
PMID25174850 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Chemical References
  • Biomarkers
  • Brain-Derived Neurotrophic Factor
  • Adult
  • Asian Continental Ancestry Group
  • Biomarkers (blood)
  • Brain-Derived Neurotrophic Factor (blood)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Schizophrenia (blood, diagnosis)
  • Severity of Illness Index

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